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Zhuhai Aoshun Medicine Co., Ltd.

Tablet Pills, Medicial Pills, Medicine manufacturer / supplier in China, offering High Quality Medicial Cimetidine Tablets / Pills, Amoxicillin Packing Box, Hot Sale Sterile Water in Glass Bottle or Plastic Bottle and so on.

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High Quality Medicial Cimetidine Tablets / Pills

FOB Price: Get Latest Price
Min. Order: 100 bottles
Production Capacity: 5000bottles/Year
Transport Package: 200mg/Bottle
Payment Terms: T/T, Western Union

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Basic Info
  • Model NO.: aoshun-tablet
  • Grade Standard: Medicine Grade
  • State: Solid
  • Cimetidine Tablets: 200mg/Box
  • Medicine Grade: Attention to The Dosage
  • Specification: GMP
  • Certification: GMP
  • Type: Chemical Reagent
  • Volatile: Not Volatile
  • Short-Term Treatment of Duodenal Ulcer: Treatment of Pathological Hypersecretory
  • Trademark: Aoshun
  • Origin: China
Product Description

                                                                                         Cimetidine Tablets

Product:

Cimetidine tablets

Ingredient:

Each tablet, for oral administration, contains 200 mg, 300 mg, 400 mg or 800 mg cimetidine, USP.

Specification:

200mg/box

Pharmaceutical form

Tablets

Therapeutic indications:

Cimetidine Tablets are indicated in:
 
(1) Short-term treatment of active duodenal ulcer. Most patients heal within 4 weeks and there is rarely reason to use Cimetidine Tablets at full dosage for longer than 6 to 8 weeks (see DOSAGE AND ADMINISTRATION: Duodenal Ulcer). Concomitant antacids should be given as needed for relief of pain. However, simultaneous administration of Cimetidine Tablets and antacids is not recommended, since antacids have been reported to interfere with the absorption of cimetidine.
 
(2) Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of active ulcer. Patients have been maintained on continued treatment with Cimetidine Tablets 400 mg at bedtime for periods of up to 5 years.
 
(3) Short-term treatment of active benign gastric ulcer. There is no information concerning usefulness of treatment periods of longer than 8 weeks.
 
(4) Erosive gastroesophageal reflux (GERD). Erosive esophagitis diagnosed by endoscopy. Treatment is indicated for 12 weeks for healing of lesions and control of symptoms. The use of Cimetidine Tablets beyond 12 weeks has not been established (see DOSAGE AND ADMINISTRATION: GERD).
 
(5) The treatment of pathological hypersecretory conditions (i.e., Zollinger-Ellison Syndrome, systemic mastocytosis, multiple endocrine adenomas).

Posology and method of administration

Duodenal Ulcer
 
Active Duodenal Ulcer
Clinical studies have indicated that suppression of nocturnal acid is the most important factor in duodenal ulcer healing (see CLINICAL PHARMACOLOGY: Antisecretory Activity: Acid Secretion). This is supported by recent clinical trials (see CLINICAL TRIALS: Duodenal Ulcer: Active Duodenal Ulcer). Therefore, there is no apparent rationale, except for familiarity with use, for treating with anything other than a once daily at bedtime dosage regimen.
 
In a U.S. dose-ranging study of 400 mg at bedtime, 800 mg at bedtime and 1600 mg at bedtime, a continuous dose-response relationship for ulcer healing was demonstrated.
 
However, 800 mg at bedtime is the dose of choice for most patients, as it provides a high healing rate (the difference between 800 mg at bedtime and 1600 mg at bedtime being small), maximal pain relief, a decreased potential for drug interactions (see PRECAUTIONS: Drug Interactions) and maximal patient convenience. Patients unhealed at 4 weeks, or those with persistent symptoms, have been shown to benefit from 2 to 4 weeks of continued therapy.
 
It has been shown that patients who both have an endoscopically demonstrated ulcer larger than 1 cm and are also heavy smokers (i.e., smoke one pack of cigarettes or more per day) are more difficult to heal. There is some evidence which suggests that more rapid healing can be achieved in this subpopulation with 1600 mg of Cimetidine Tablets at bedtime. While early pain relief with either 800 mg at bedtime or 1600 mg at bedtime is equivalent in all patients, 1600 mg at bedtime provides an appropriate alternative when it is important to ensure healing within 4 weeks for this subpopulation. Alternatively, approximately 94% of all patients will also heal in 8 weeks with 800 mg of Cimetidine Tablets at bedtime
 
Other regimens of Cimetidine Tablets in the United States which have been shown to be effective are: 300 mg 4 times daily, with meals and at bedtime, the original regimen with which U.S. physicians have the most experience, and 400 mg twice daily, in the morning and at bedtime (see CLINICAL TRIALS: Duodenal Ulcer: Active Duodenal Ulcer).
 
Concomitant antacids should be given as needed for relief of pain. However, simultaneous administration of Cimetidine Tablets and antacids is not recommended, since antacids have been reported to interfere with the absorption of cimetidine.
 
While healing with Cimetidine Tablets often occurs during the first week or two, treatment should be continued for 4 to 6 weeks unless healing has been demonstrated by endoscopic examination.
 
Maintenance Therapy for Duodenal Ulcer
In those patients requiring maintenance therapy, the recommended adult oral dose is 400 mg at bedtime.
 
Active Benign Gastric Ulcer
 
The recommended adult oral dosage for short-term treatment of active benign gastric ulcer is 800 mg at bedtime, or 300 mg 4 times a day with meals and at bedtime. Controlled clinical studies were limited to 6 weeks of treatment (see CLINICAL TRIALS). A dose of 800 mg at bedtime is the preferred regimen for most patients based upon convenience and reduced potential for drug interactions. Symptomatic response to Cimetidine Tablets does not preclude the presence of a gastric malignancy. It is important to follow gastric ulcer patients to assure rapid progress to complete healing.
 
Erosive Gastroesophageal Reflux Disease (GERD)
 
The recommended adult oral dosage for the treatment of erosive esophagitis that has been diagnosed by endoscopy is 1600 mg daily in divided doses (800 mg twice daily or 400 mg 4 times daily) for 12 weeks. The use of Cimetidine Tablets beyond 12 weeks has not been established.
 
Pathological Hypersecretory Conditions (such as Zollinger-Ellison Syndrome)
 
Recommended adult oral dosage: 300 mg 4 times a day with meals and at bedtime. In some patients it may be necessary to administer higher doses more frequently. Doses should be adjusted to individual patient needs, but should not usually exceed 2400 mg per day and should continue as long as clinically indicated.
 
Dosage Adjustment for Patients with Impaired Renal Function
 
Patients with severely impaired renal function have been treated with Cimetidine Tablets. However, such usage has been very limited. On the basis of this experience the recommended dosage is 300 mg every 12 hours orally. Should the patient's condition require, the frequency of dosing may be increased to every 8 hours or even further with caution. In severe renal failure, accumulation may occur and the lowest frequency of dosing compatible with an adequate patient response should be used. When liver impairment is also present, further reductions in dosage may be necessary. Hemodialysis reduces the level of circulating cimetidine. Ideally, the dosage schedule should be adjusted so that the timing of a scheduled dose coincides with the end of hemodialysis.

Contraindications:

Cimetidine Tablets are contraindicated for patients known to have hypersensitivity to the product.

Shelf Life:

Three years.

Storage:

Store at 20° to 25°C (68° to 77°F). [See USP Controlled Room Temperature.
Protect from light.

Package

We can do as ur requirement or can use our own package

Remark:

OEM available



Company Information:
Our company is specialized in all kinds of pharmaceutical finished products (Capsules, tablets, oral suspension, injection, etc), Pharmaceutical raw material (powder, particle, liquid, etc), Health food and some medical consumables (Especially for disposable syringes and wheelchairs, which have got GS, GMP, CE, ... certificates). And recently, we have expanded our business range to some other products including capsule coffee, slimming tea, Chinese Medicine (Raw material & Extract & Essence), herbal beauty products....
Also, we have our own manufacturer as well as quite a few cooperative factories. And our manufacturer was founded in the 1950s with almost 50years of history in pharmaceutical production in China. It has over 200 drug production approvals issued by SFDA & some of our health-food r certificated with FDA. In addition, we can offer professional OEM service, too if the quantity is enough.

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To get more information, please feel free to contact with us.
Zhuhai Aoshun Medicine Co.,Ltd.
Tel: 0086-0756-6832013
Fax: 0086-0756-6832003
Web: http://www.aoshunfa.com/
          http://www.aoshun.en.alibaba.com/
          http://aoshun.en.made-in-china.com/
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